Bestrophin 3 antibody

Catalog No. ABIN2746310

This Rabbit Polyclonal antibody specifically detects Bestrophin 3 in WB, ELISA, IF, IHC, IP and CM. It exhibits reactivity toward Human, Cow and Monkey and has been mentioned in 6+ publications.

Quick Overview for Bestrophin 3 antibody (ABIN2746310)

Target: Bestrophin 3 (BEST3)

Reactivity: Human, Cow, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bestrophin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Confocal Microscopy (CM)

Product Details anti-Bestrophin 3 Antibody

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to unique amino acid sequence on mouse Bestrophin 3 protein.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.75-1.20 μg/μL

References for anti-Bestrophin 3 antibody (ABIN2746310)

Golubinskaya, Elvin, Ebefors, Gustafsson, Mallard, Nyström, Nilsson: "Bestrophin-3 is differently expressed in normal and injured mouse glomerular podocytes." in: Acta physiologica (Oxford, England), Vol. 214, Issue 4, pp. 481-96, (2015) (PubMed).

Jiang, Liu, Ma, Tang, Zhou, Guan: "Mitochondria dependent pathway is involved in the protective effect of bestrophin-3 on hydrogen peroxide-induced apoptosis in basilar artery smooth muscle cells." in: Apoptosis : an international journal on programmed cell death, Vol. 18, Issue 5, pp. 556-65, (2013) (PubMed).

Wang, Yang, Zheng, Zhang, Tang, Wang, Du, Lv, Liu, Zhou, Guan: "Downregulation of TMEM16A calcium-activated chloride channel contributes to cerebrovascular remodeling during hypertension by promoting basilar smooth muscle cell proliferation." in: Circulation, Vol. 125, Issue 5, pp. 697-707, (2012) (PubMed).

Lee, Chakraborty, Roussa, Wolff, Thévenod: "ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP." in: Biochimica et biophysica acta, Vol. 1823, Issue 10, pp. 1864-76, (2012) (PubMed).

Broegger, Jacobsen, Secher Dam, Boedtkjer, Kold-Petersen, Pedersen, Aalkjaer, Matchkov: "Bestrophin is important for the rhythmic but not the tonic contraction in rat mesenteric small arteries." in: Cardiovascular research, Vol. 91, Issue 4, pp. 685-93, (2011) (PubMed).

Matchkov, Larsen, Bouzinova, Rojek, Boedtkjer, Golubinskaya, Pedersen, Aalkjaer, Nilsson: "Bestrophin-3 (vitelliform macular dystrophy 2-like 3 protein) is essential for the cGMP-dependent calcium-activated chloride conductance in vascular smooth muscle cells." in: Circulation research, Vol. 103, Issue 8, pp. 864-72, (2008) (PubMed).

Target Details for Bestrophin 3

Target: Bestrophin 3 (BEST3)

Alternative Name: Bestrophin 3

UniProt: Q6H1V1